In a time where uncertainty is imminent in all realms of life, we must be prepared to confront norms, challenge stereotypes, and welcome change. We live in an era where a critical and creative mind is integral in order to defy what the odds tell us, make a different in our world, and take a leap of faith. For some, this might mean a shift in attitude; for others, it might mean a questioning and examination of preconceived notions. Instead of accepting the norm, bold individuals who walk the unlikely path and introduce unlikely ideas find themselves achieving unprecedented outcomes. Those who have bested the probabilities are the leaders, scientists, and innovators who have, in their own way, changed the ways of our world today. In TEDx, we invite those who have met, achieved, conquered, or created “the unlikely” in their fields to share their ideas. Their experiences in the face of the likely in tandem with an active resistance to conformity will inspire our community in facing the personal and global challenges to come.